Safety Data Sheets of D-Calcium Pantothenate(Vitamin B5)
Section 1: Chemical Product and Company Identification
Product Name: Calcium pantothenate
Catalog Codes: SLC5035, SLC2245
TSCA: TSCA 8(b) inventory: Calcium pantothenate
CI#: Not available.
Synonym: Vitamin B5; D-Pantothenic acid calcium salt;(+)-Pantothenic
acid calcium salt; (R)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-B-alanine
Chemical Name: d-Calcium Pantothenate
Chemical Formula: C18H32CaN2O10
2: Composition and Information on Ingredients
Data on Ingredients: Calcium pantothenate: ORAL (LD50): Acute:
>10000 mg/kg [Mouse]. >10000mg/kg [Rat].
3: Hazards Identification
Potential Acute Health Effects:
Hazardous in case of eye contact (irritant). Slightly hazardous
in case of skin contact (irritant, permeator), of ingestion, of
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged exposure is not known to aggravate medical
4: First Aid Measures
Check for and remove any contact lenses. In case of contact, immediately
flush eyes with plenty of water for at least 15 minutes. Cold
water may be used. Get medical attention.
Wash with soap and water. Cover the irritated skin with an emollient.
Get medical attention if irritation develops. Cold water may be
Serious Skin Contact: Not available.
Inhalation: If inhaled, remove to fresh air. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen.
Get medical attention.
Serious Inhalation: Not available.
Do NOT induce vomiting unless directed to do so by medical personnel.
Never give anything by mouth to an unconscious person. Loosen
tight clothing such as a collar, tie, belt or waistband. Get medical
attention if symptoms appear.
Serious Ingestion: Not available.
5: Fire and Explosion Data
Flammability of the Product: May be combustible at high temperature.
Auto-Ignition Temperature: Not available.
Flash Points: CLOSED CUP: Higher than 93.3 degree C(200 degree
Flammable Limits: Not available.
Products of Combustion: These products are carbon oxides (CO,
CO2), nitrogen oxides (NO, NO2...). Some metallic oxides.
Fire Hazards in Presence of Various Substances:
Slightly flammable to flammable in presence of open flames and
sparks, of heat. Non-flammable in presence of shocks.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact:
Risks of explosion of the product in presence of static discharge:
Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards: Not available.
Section 6: Accidental Release Measures
Use appropriate tools to put the spilled solid in a convenient
waste disposal container. Finish cleaning by spreading water on
the contaminated surface and dispose of according to local and
regional authority requirements.
Use a shovel to put the material into a convenient waste disposal
container. Finish cleaning by spreading water on the contaminated
surface and allow to evacuate through the sanitary system.
7: Handling and Storage
Keep away from heat. Keep away from sources of ignition. Empty
containers pose a fire risk, evaporate the residue under a fume
hood. Ground all equipment containing material. Do not ingest.
Do not breathe dust. Avoid contact with eyes. Wear suitable protective
clothing. If ingested, seek medical advice immediately and show
the container or the label. Keep away from incompatibles such
as acids, alkalis.
Light Sensitive. Hygroscopic. Store in light-resistant containers.
Keep container tightly closed. Keep container in a cool, well-ventilated
area. Do not store above 24degree C (75.2degree F). Preferably
store in refrigerator.
8: Exposure Controls/Personal Protection
Use process enclosures, local exhaust ventilation, or other engineering
controls to keep airborne levels below recommended exposure limits.
If user operations generate dust, fume or mist, use ventilation
to keep exposure to airborne contaminants below the exposure limit.
Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified
respirator or equivalent. Gloves.
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self
contained breathing apparatus should be used to avoid inhalation
of the product. Suggested protective clothing might not be sufficient;
consult a specialist BEFORE handling this product.
Exposure Limits: Not available.
9: Physical and Chemical Properties
Physical state and appearance: Solid. (Solidcrystalline powder.)
Odor: Almost Odorless.
Taste: Sweetish with bitter aftertaste
Molecular Weight: 476.54 g/mole
PH (1% soln/water): Not available.
Boiling Point: Not available.
Melting Point: 195degree C (383degree F)
Critical Temperature: Not available.
Specific Gravity: 0.6 (Water = 1)
Vapor Pressure: Not applicable.
Vapor Density: Not available.
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff.: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: See solubility in water, methanol, acetone.
Soluble in cold water, hot water, methanol, acetone, glycerin.
Very slightly soluble in diethyl ether.
Moderately soluble in Ethanol.
Virtually incoluble in chloroform.
Section 10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Not available.
Incompatibility with various substances: Reactive with acids,
Corrosivity: Non-corrosive in presence of glass.
Special Remarks on Reactivity: Hygroscopic. Light Sensitive
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
Section 11: Toxicological Information
Routes of Entry: Inhalation. Ingestion.
Toxicity to Animals: Acute oral toxicity (LD50): >10000 mg/kg
Chronic Effects on Humans: Not available.
Other Toxic Effects on Humans: Slightly hazardous in case of skin
contact (irritant, permeator), of ingestion, of inhalation.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: Not available.
Special Remarks on other Toxic Effects on Humans:
Acute Potential Health Effects:
Skin: May cause skin irritation. May affect behavior and respiratory
if absorbed through skin (as indicated by subcutaneous LD50 data
in RTECS. However, absorption is not likely.
Eyes: Dust may cause mechanical eye irritation.
Inhalation: Dust may cause respiratory tract irritation.
Ingestion: Low hazard for usual industrial handling. Although
unlikely, it may cause digestive tract disturbances.
12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely.
However, long term egradation products may arise.
Toxicity of the Products of Biodegradation: The product itself
and its products of degradation are not toxic.
Special Remarks on the Products of Biodegradation: Not available.
Section 13: Disposal Considerations
Waste must be disposed of in accordance with federal, state and
local environmental control regulations.
Section 14: Transport Information
DOT Classification: Not a DOT controlled material (United States).
Identification: Not applicable.
Special Provisions for Transport: Not applicable.
Section 15: Other Regulatory Information
Federal and State Regulations: TSCA 8(b) inventory: Calcium pantothenate
Other Regulations: EINECS: This product is on the European Inventory
of Existing Commercial Chemical Substances.
WHMIS (Canada): Not controlled under WHMIS (Canada).
R36- Irritating to eyes.
S2- Keep out of the reach of children.
S46- If swallowed, seek medical advice
immediately and show this container or label.
Health Hazard: 1
Fire Hazard: 1
Personal Protection: E
National Fire Protection Association (U.S.A.):
Dust respirator. Be sure to use an approved/certified respirator
Section 16: Other Information
References: Not available.
Other Special Considerations: Not available