Safety Data Sheets of D-Panthenol
Section 1: Chemical Product and Company Identification
Product Name: D (+)-Pantothenyl Alcohol
Catalog Codes: SLD3925
TSCA: TSCA 8(b) inventory: D (+)-Pantothenyl Alcohol
CI#: Not available.
Synonym: Panthenol; D(+)- Panthenol; Dexpanthenol; D-Panthenol;
Chemical Name: Dexpanthenol
Chemical Formula: C9-H19-N-O4
2: Composition and Information on Ingredients
Toxicological Data on Ingredients: Not applicable.
3: Hazards Identification
Potential Acute Health Effects: Slightly hazardous in case of
skin contact (irritant), of eye contact (irritant), of ingestion,
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged exposure is not known to aggravate medical
4: First Aid Measures
Eye Contact: Check for and remove any contact lenses. In case
of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Cold water may be used. Get medical attention
if irritation occurs.
Skin Contact: Wash with soap and water. Cover the irritated skin
with an emollient. Get medical attention if irritation develops.
Cold water may be used.
Serious Skin Contact: Not available.
Inhalation: If inhaled, remove to fresh air. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen.
Get medical attention.
Serious Inhalation: Not available.
Ingestion: Do NOT induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Loosen tight clothing such as a collar, tie, belt or waistband.
Get medical attention if symptoms appear.
Serious Ingestion: Not available.
5: Fire and Explosion Data
Flammability of the Product: May be combustible at high temperature.
Auto-Ignition Temperature: Not available.
Flash Points: Not available.
Flammable Limits: Not available.
Products of Combustion: These products are carbon oxides (CO,
CO2), nitrogen oxides (NO, NO2...).
Fire Hazards in Presence of Various Substances: Slightly flammable
to flammable in presence of open flames and sparks, of heat. Non-flammable
in presence of shocks.
Explosion Hazards in Presence of Various Substances: Risks of
explosion of the product in presence of mechanical impact: Not
available. Risks of explosion of the product in presence of static
discharge: Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards: Not available.
6: Accidental Release Measures
Dilute with water and mop up, or absorb with an inert dry material
and place in an appropriate waste disposal container. Finish cleaning
by spreading water on the contaminated surface and dispose of
according to local and regional authority requirements.
Absorb with an inert material and put the spilled material in
an appropriate waste disposal. Finish cleaning by spreading water
on the contaminated surface and allow to evacuate through the
7: Handling and Storage
Keep away from heat. Keep away from sources of ignition. Empty
containers pose a fire risk, evaporate the residue under a fume
hood. Ground all equipment containing material. Do not ingest.
Do not breathe gas/fumes/vapor/spray. If ingested, seek medical
advice immediately and show the container or the label. Keep away
from incompatibles such as oxidizing agents, acids, alkalis.
Hygroscopic. Keep container tightly closed. Keep container in
a cool, well-ventilated area. Do not store above 25 degree C.
8: Exposure Controls/Personal Protection
Engineering Controls: Provide exhaust ventilation or other engineering
controls to keep the airborne concentrations of vapors below their
respective threshold limit value. Ensure that eyewash stations
and safety showers are proximal to the work-station location.
Protection:Safety glasses. Lab coat. Dust respirator. Be sure
to use an approved/certified respirator or equivalent. Gloves
Protection in Case of a Large Spill:Splash goggles. Full suit.
Dust respirator. Boots. Gloves. A self contained breathing apparatus
should be used to avoid inhalation of the product. Suggested protective
clothing might not be sufficient; consult a specialist BEFORE
handling this product.
Exposure Limits: Not available.
9: Physical and Chemical Properties
Physical state and appearance: Liquid. (Viscous liquid.)
Odor: Not available.
Taste: Bitter. (Slight.)
Molecular Weight: 205.25 g/mole
Color: Clear Colorless.
pH (1% soln/water): Not available.
Boiling Point: Decomposition temperature: 119¡ãC
Melting Point: Not available.
Critical Temperature: Not available.
Specific Gravity: 1.2 (Water = 1)
Vapor Pressure: Not available.
Vapor Density: 7.08 (Air = 1)
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff.: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: See solubility in water, methanol.
Solubility: Easily soluble in cold water, methanol.Very slightly
soluble in diethyl ether.Very soluble in ethanol.
10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Excess heat, moisture, incompatible
Incompatibility with various substances:
Reactive with oxidizing agents, acids, alkalis. Slightly reactive
to reactive with moisture.
Corrosivity: Not available.
Special Remarks on Reactivity:
Hygroscopic. Incompatible with alkalis and strong acids, and strong
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
11: Toxicological Information
Routes of Entry: Absorbed through skin. Eye contact.
Toxicity to Animals: Acute oral toxicity (LD50): 15000 mg/kg [Mouse].
Chronic Effects on Humans: Not available.
Other Toxic Effects on Humans: Slightly hazardous in case of skin
contact (irritant), of ingestion, of inhalation.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: Not available.
Special Remarks on other Toxic Effects on Humans:
Acute Potential Health Effects:
Skin: Causes skin irritation.
Eyes: Causes eye irritation.
Inhalation: Inhalation of vapor causes respiratory tract irritation.
Ingestion: Ingestion of large amounts may cause gastrointestinal
tract irritation with nausea, vomiting and diarrhea.
12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely.
However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The product itself
and its products of degradation are not toxic.
Special Remarks on the Products of Biodegradation: Not available.
13: Disposal Considerations
Waste must be disposed of in accordance with federal, state and
local environmental control regulations.
14: Transport Information
DOT Classification: Not a DOT controlled material (United States).
Identification: Not applicable.
Special Provisions for Transport: Not applicable.
15: Other Regulatory Information
Federal and State Regulations:
TSCA 8(b) inventory: Dexpanthenol
SARA 313 toxic chemical notification and release reporting: Dexpanthenol
Other Regulations: EINECS: This product is on the European Inventory
of Existing Commercial Chemical Substances.
WHMIS (Canada): Not controlled under WHMIS (Canada).
DSCL (EEC): This product is not classified according to the EU
Health Hazard: 1
Fire Hazard: 1
Personal Protection: E
National Fire Protection Association (U.S.A.):
Dust respirator. Be sure to use an approved/certified respirator
16: Other Information
References: Not available.
Other Special Considerations: Not available.