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 SODIUM PYRUVATE

SYNONYMS:

Natriumpyruvat; Piruvato de sodio; Pyruvate de sodium;2-Oxopropanoic acid, sodium salt;
Pyruvic Acid Sodium Salt;

 

 

CAS NO.:

113-24-6

 

EINECS NO.:

204-024-4

 

FORMULA:

CH3COCOONa

 

H.S. CODE:

2918.30

 

CLASS NO.:

N/A

 

UN NO.:

N/A

 

NFPA:

2-1-0-E

 

DESCRIPTION:

white to off-white crystalline powder. Pyruvic acid is a liquid with acetic-acid smell; melting point 11 - 12 C; solube in water. It occurs naturally as an intermediate product in carbohydrate and protein metabolism in the body. The six-carbon glucose molecule is broken down to two molecules of pyruvic acid in aerobic condition as the main input for Krebs cycle, whereas to two molecules of lactic acid (alpha hydroxy acid) in anaerobic condition. Krebs cycle (also called citric acid cycle; tricarboxylic acid cycle) is a sequent process of enzymatic reaction which a two-carbon acetyl unit is oxidized to carbon dioxide and water to provide energy in the form of high-energy phosphate bonds.

 

APPLICATION

In commercial, pyruvic acid is used to produce its salts and esters (pyruvates) for the use as dietary supplements of the effective weight loss enhancers . Pyruvic acid is used for the synthesis of amino acids (alanine, tyrosine, phenylalanine, and tryptophan) and used in biochemical research. Its derivatives are used in making food additives and flavoring agents.

SPECIFICATION & PACKING

APPEARANCE: white to off-white crystalline powder

ASSAY: 99.0% min

LOSS ON DRYING: 1.0% max

HEAVY METALS: 10ppm max

CHLORIDE: 30ppm max

SULFATE ASH: 0.01% max

WATER: 0.5% max

Packing: 25g,50g.

Storage: Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly closed. Keep in a cool, well-ventilated place. Combustible materials should be stored away from extreme heat and away from strong oxidizing agent

RAW MATERIAL:

N/A

END GOODS:

N/A

REMARKS:

N/A

MATERIAL SAFE DATA SHEETS

Section 1: Chemical Product and Company Identification

Product Name: Sodium pyruvate

CAS#: 113-24-6

Synonym: Natriumpyruvat; Piruvato de sodio; Pyruvate de sodium;
2-Oxopropanoic acid, sodium salt; Pyruvic Acid Sodium Salt;

Chemical Formula: C3H3NaO3


Section 2: Composition and Information on Ingredients

Composition:

Name             CAS #         % by Weight

Sodium pyruvate   113-24-6          100

Toxicological Data on Ingredients: Sodium pyruvate LD50: Not available. LC50: Not available.

Section 3: Hazards Identification

Potential Acute Health Effects:

Very hazardous in case of ingestion. Hazardous in case of skin contact (irritant), of inhalation. Slightly hazardous in case of eye contact (irritant).

Potential Chronic Health Effects:

Very hazardous in case of ingestion.

Hazardous in case of skin contact (irritant), of inhalation.

Slightly hazardous in case of eye contact (irritant).

CARCINOGENIC EFFECTS: Not available.

MUTAGENIC EFFECTS: Not available.

TERATOGENIC EFFECTS: Not available.

DEVELOPMENTAL TOXICITY: Not available.

Section 4: First Aid Measures

Eye Contact: Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used.

Skin Contact:

After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin.Cold water may be used. Cover the irritated skin with an emollient. If irritation persists, seek medical attention.Wash contaminated clothing before reusing.

Serious Skin Contact:

Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical

attention.

Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention.

Serious Inhalation: Not available.

Ingestion:

Do not induce vomiting. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not

breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention.

Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: May be combustible at high temperature.

Auto-Ignition Temperature: Not available.

Flash Points: Not available.

Flammable Limits: Not available.

Products of Combustion: These products are carbon oxides (CO, CO2). Some metallic oxides.

Fire Hazards in Presence of Various Substances: Not available.

Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of mechanical impact: Not available.

Risks of explosion of the product in presence of static discharge: Not available.

Fire Fighting Media and Instructions:

SMALL FIRE: Use DRY chemical powder.

LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Special Remarks on Fire Hazards: Not available.

Special Remarks on Explosion Hazards: Not available.

Section 6: Accidental Release Measures

Small Spill:

Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by

spreading water on the contaminated surface and dispose of according to local and regional authority

requirements.

Large Spill:

Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water

on the contaminated surface and allow to evacuate through the sanitary system.


Section 7: Handling and Storage

Precautions:

Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the

residue under a fume hood. Ground all equipment containing material. Do not breathe dust. Avoid contact with skin Wear suitable protective clothing In case of insufficient ventilation, wear suitable respiratory equipment If you feel unwell, seek medical attention and show the label when possible.

Storage:

Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly

closed. Keep in a cool, well-ventilated place. Combustible materials should be stored away from extreme heat

and away from strong oxidizing agents.

Section 8: Exposure Controls/Personal Protection

Engineering Controls:

Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below

recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to

airborne contaminants below the exposure limit.

Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.

Gloves.

Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.

Exposure Limits: Not available.

Section 9: Physical and Chemical Properties

Physical state and appearance: Solid. (Crystalline solid.)

Odor: Not available.

Taste: Not available.

Molecular Weight: 110.05 g/mole

Color: White.

pH (1% soln/water): Not available.

Boiling Point: Not available.

Melting Point: Decomposes.

Critical Temperature: Not available.

Specific Gravity: Not available.

Vapor Pressure: Not applicable.

Vapor Density: Not available.

Volatility: Not available.

Odor Threshold: Not available.

Water/Oil Dist. Coeff.: Not available.

Ionicity (in Water): Not available.

Dispersion Properties: See solubility in water.

Solubility: Easily soluble in cold water.

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Not available.

Incompatibility with various substances: Not available.

Corrosivity: Non-corrosive in presence of glass.

Special Remarks on Reactivity: Not available.

Special Remarks on Corrosivity: Not available.

Polymerization: No.

Section 11: Toxicological Information

Routes of Entry: Inhalation. Ingestion.

Toxicity to Animals:

LD50: Not available.

LC50: Not available.

Chronic Effects on Humans: Not available.

Other Toxic Effects on Humans:

Very hazardous in case of ingestion.

Hazardous in case of skin contact (irritant), of inhalation.

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans: Not available.

Special Remarks on other Toxic Effects on Humans: Not available.

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:

Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.

Toxicity of the Products of Biodegradation: The products of degradation are more toxic.

Special Remarks on the Products of Biodegradation: Not available.

Section 13: Disposal Considerations

Waste Disposal:

Section 14: Transport Information

DOT Classification: Not a DOT controlled material (United States).

Identification: Not applicable.

Special Provisions for Transport: Not applicable.

Section 15: Other Regulatory Information

Federal and State Regulations: TSCA 8(b) inventory: Sodium pyruvate

Other Regulations: Not available..

Other Classifications:

WHMIS (Canada): Not controlled under WHMIS (Canada).

DSCL (EEC): R38- Irritating to skin.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 1

Reactivity: 0

Personal Protection: E

National Fire Protection Association (U.S.A.):

Health: 2

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment:

Gloves.

Lab coat.

Dust respirator. Be sure to use an approved/certified respirator or equivalent.

Safety glasses.

Section 16: Other Information

References: Not available.

Other Special Considerations: Not available.

SPECIAL DESCRIPTION

Pyruvic acid is a low mole weight alpha keto acid (ketone along with carboxylic acid). It contains a ketone bond on the carbon atom next to the acid group. If the ketone is on the second carbon next to the acid group, it is called beta-keto acid.

Members of alpha-keto acid

alpha-keto acid

CAS RN

Pyruvic acid

127-17-3

Phenylpyruvic acid

156-06-9

4-Hydroxyphenylpyruvic acid

156-39-8

Glyoxylic acid

298-12-4

alpha-Ketoglutaric acid

328-50-7

Oxalacetic acid

328-42-7

Indol-3-ylpyruvic acid

392-12-1

2-Keto-L-gulonic acid

526-98-7

Phthalonic acid

528-46-1

2-Keto-4-methylthiobutyric acid

583-92-6

alpha-Ketobutyric acid

600-18-0

Phenylglyoxylic acid

611-73-4

Phenylglyoxylic acid

611-73-4

alpha-Ketoisovalerate

759-05-7

Hydroxydiiodophenylpyruvic acid

780-00-7

alpha-Ketoisocaproic acid

816-66-0

3-Deoxy-2-octulosonic acid

1069-03-0

Vanilpyruvic acid

1081-71-6

2-Hydroxy-4-oxopentanedioic acid

1187-99-1

alpha-Keto-beta-methylvaleric acid

1460-34-0

alpha-Oxofuran-2-acetic acid

1467-70-5

2-Ketopentanoic acid

1821-02-9

beta-Hydroxy-alpha-ketobutyric acid

1944-42-9

Vanilglycolic acid

2021-40-1

alpha-Ketocaproic acid

2492-75-3

3-Deoxy-D-arabino-2-heptulosonic acid 7-phosphate

2627-73-8

alpha-Ketoadipic acid

3184-35-8

alpha-Keto-delta-guanidinovaleric acid

3715-10-4

alpha-Oxothiophen-2-acetic acid

4075-59-6

3,4-Dihydroxyphenylpyruvic acid

4228-66-4

2-Keto-4-mercaptobutyric acid

4273-28-3

alpha-Oxocyclohexaneacetic acid

4354-49-8

2-Nitrophenylpyruvic acid

5461-32-5

Ketohypoglycin

5746-24-7

3,4-Didehydro-2-ketoglutaric acid

6004-32-6

4-chloro-alpha-oxobenzeneacetic acid

7099-88-9

4-Methylbenzoylformic acid

7163-50-0

3-Deoxy-2-ketoarabinonic acid

7636-04-6

Amidinophenylpyruvic acid

10290-63-8

4-Hydroxyphenylglyoxylic acid

15573-67-8

Provitamin C

16533-48-5

4-Aminophenylpyruvic acid

16921-36-1

3-Deoxy-D-erythro-2-hexulosonic acid

17510-99-5

4-(((Aminoiminomethyl)amino)oxy)-2-oxobutanoic acid

17774-31-

5-Amino-2,5-dioxopentanoic acid

18465-19-5

2-Ketogluconate

20248-27-5

2-Keto-4-pentenoic acid

20406-62-6

3-Deoxyglycero-galactononulosonic acid

22594-61-2

Ketomycin

23364-22-9

N-Acetylisatic acid

32375-61-4

N-4-Chlorobenzoylisatinic acid

54778-24-4

N-Benzoylisatinic acid

54778-23-3

2-Keto-3-butynoic acid

56842-75-2

2-Keto-3-deoxyoctonic acid 5-phosphate

57717-01-8

2-Oxo-4-hydroxyarginine

64186-82-9

2-Keto-3-bromobutanoic acid

71183-36-3

alpha-Ketokainic acid

75232-58-5

3-Bromo-2-ketopentanedioic acid

76444-16-1

alpha-Ketosuberic acid

96406-05-2

2-Keto-3-deoxy-1,7-dicarboxyheptonic acid

99778-26-4

4-(chloromethyl)-alpha-oxobenzeneacetic acid

114996-73-5

5-Hydroxy-6-(2-keto-3-thiopropionyl)-7,9,11,14-eicosatetraenoic acid

117675-20-4

Clavicoronic acid

139748-98-4