Safety Data Sheets of Hydroxypropyl methyl cellulose (HPMC)
Section 1 - Chemical Product
MSDS Name: Hydroxypropyl Methyl Cellulose
2 - Company Identification
Molecular Formula£ÜC6H7O2(OH)x(OCH3)y(OC3H7)z x+y+z=3
CAS# Chemical Name Percent EINECS/ELINCS
9004-65-3 Hydroxypropyl Methyl Cellulose - unlisted
3 - Hazards Identification
Hazard Symbols: None listed.
Risk Phrases: None listed.
Appearance: white to off-white powder. Caution! The toxicological
properties of this material have not been fully investigated.
May cause eye and skin irritation. May cause respiratory and digestive
Target Organs: No data found.
Potential Health Effects
Eye: May cause eye irritation. The toxicological properties of
this material have not been fully investigated.
Skin: May cause skin irritation. The toxicological properties
of this material have not been fully
Ingestion: May cause irritation of the digestive tract. The toxicological
properties of this substance have not been fully investigated.
Inhalation: May cause respiratory tract irritation. The toxicological
properties of this substance have not been fully investigated.
Chronic: No information found.
Section 4 - First Aid Measures
Eyes: Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical
Skin: Get medical aid. Flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion: Never give anything by mouth to an unconscious person.
Get medical aid. Do NOT induce vomiting. If conscious and alert,
rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation: Remove from exposure and move to fresh air immediately.
If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing
apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent),
and full protective gear. During a fire, irritating and highly
toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media: Use agent most appropriate to extinguish
fire. Use water spray, dry chemical, carbon dioxide, or appropriate
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 0; Instability:
General Information: Use proper personal protective equipment
as indicated in Section 8.
Spills/Leaks: Clean up spills immediately, observing precautions
in the Protective Equipment
section. Sweep up, then place into a suitable container for disposal.
Avoid generating dusty conditions. Provide ventilation.
Section 6 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated
clothing and wash before reuse. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with
eyes, skin, and clothing. Keep container tightly closed. Avoid
ingestion and inhalation.
Storage: Store in a tightly closed container. Store in a cool,
dry, well-ventilated area away from incompatible substances.
Section 7 - Exposure Controls, Personal Protection
Engineering Controls: Use adequate ventilation to keep airborne
Chemical Name ACGIH NIOSH OSHA - Final PELs
Hydroxypropyl Methyl Cellulose none listed none listed none listed
OSHA Vacated PELs: Hydroxypropyl Methyl Cellulose: No OSHA Vacated
PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety
goggles as described by OSHA's eye and face protection regulations
in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin
Respirators: Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Always use a NIOSH or
European Standard EN 149 approved respirator when necessary.
Section 8 - Physical and Chemical Properties
Physical State: Powder
Appearance: white to off-white
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Specific Gravity/Density:Not available.
Molecular Formula:Not available.
Molecular Weight:Not available.
Section 9 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, dust generation,
excess heat, strong oxidants.
Incompatibilities with Other Materials: Oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, irritating
and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 10 - Toxicological Information
RTECS#: CAS# 9004-65-3: NF9125000
LD50/LC50: Not available.
Carcinogenicity: CAS# 9004-65-3: Not listed by ACGIH, IARC, NIOSH,
NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: No data available.
Section 11 - Ecological Information
No information available.
Section 12 - Disposal Considerations
discarded chemical is classified as a hazardous waste. US EPA
guidelines for the classification determination are listed in
40 CFR Parts 261.3. Additionally, waste generators must consult
state and local hazardous waste regulations to ensure complete
and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 13 - Transport Information
DOT IATA RID/ADR IMO Canada TDG
Shipping Name: No information available. No information available.
14 - Regulatory Information
CAS# 9004-65-3 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This
material does not contain any Class 1 Ozone depletors. This material
does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous
Substances under the CWA. None of the chemicals in this product
are listed as Priority Pollutants under the CWA. None of the chemicals
in this product are listed as Toxic Pollutants under the CWA.
None of the chemicals in this product are considered highly hazardous
CAS# 9004-65-3 is not present on state lists from CA, PA, MN,
MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in
this product are listed.
European Labeling in Accordance with EC Directives
S 24/25 Avoid contact with skin and eyes.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where possible).
S 28A After contact with skin, wash immediately with
plenty of water.